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Network Modeling for Bacterial Communities

This repository is part of a summer project with Dr. Emily Davenport from Pennsylvania State University, where we developed a model to study disease dynamics in individuals. We utilized the TwinsUK dataset for this project, which includes 16S sequencing data of bacterial communities.


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This R Markdown file contains the code for generating a SPIEC-EASI network for bacterial communities using 16S sequencing data. It includes a generic workflow that can be used for network construction based on sequencing data.

  • Key Features:
    • Network generation using SPIEC-EASI (Sparse Inverse Covariance Estimation for Ecological Association Inference).
    • Designed for 16S sequencing data of bacterial communities.

This R Markdown file is still a work in progress. It contains algorithms to calculate and visualize important network statistics for the generated SPIEC-EASI network. Key metrics include:

  • Modularity
  • Transitivity
  • Centrality

These statistics help in understanding the structure and relationships within the bacterial communities.

  • Key Features:
    • Calculates various network statistics.
    • Visualizes key properties such as modularity, transitivity, and centrality.

This file contains the network visualization generated by the SPIEC-EASI modeling technique. It provides a visual representation of the bacterial community network based on the analysis.

  • Key Features:
    • Visual representation of the bacterial network.
    • Shows connections between various bacterial species based on ecological relationships inferred from the data.

SPIEC-EASI bacterial network


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SPIEC-EASI Network Modeling of Bacterial Communities (TwinsUK).

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