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@BioSymphony

BioSymphony

AI agent tools for biological research

BioSymphony

AI agent tools for biological research.

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BioSymphony builds public toolkits for using coding agents in biological research. Current toolkits cover biosynthetic route exploration, structural biology campaigns, natural-product genome mining, fermentation experiment design, and cryo-EM review.

Each toolkit ships local demos, agent skill packs, and templates for concrete outputs.

Start Here

  • BioProspector maps biosynthetic routes for target molecules: enzyme and gene candidates, pathway ideas turned into follow-up searches and experiment plans.
  • Structure Factory runs structural biology campaigns: binder design, structure mapping, candidate screening, ranking, and local or cloud run plans.
  • GeneCluster searches public plant, fungal, and microbial data sources for natural-product gene clusters, with candidate comparison and follow-up planning.
  • Ferm DoE plans fermentation and biomanufacturing experiments: design options, scale-context comparison, and run plans.
  • CryoCore drives cryo-EM review: maps and models, figure planning, state comparison, and local or cloud compute setup.

Shared across the toolkits

  • Repo-local agent instructions and skill packs.
  • Local demos that use synthetic fixtures or explicitly public inputs.
  • Setup and formatting checks for local runs.
  • Templates for search plans, experiment plans, review notes, and compute setup.
  • Paths from local demos to operator-owned cloud, HPC, or GPU resources.

Using Them with an Agent

  1. Choose the toolkit that matches your research workflow.
  2. Read the repository README.md and AGENTS.md.
  3. Run the local demo or smoke test.
  4. Give your coding agent the repo-local instructions or skill pack.

Working Style

Scientific judgment belongs with the researcher. The agent can collect context, prepare files, run routine checks, and summarize early findings. The researcher sets the question, chooses inputs, interprets outputs, and decides what belongs in the next analysis or experiment.

Begin with one research question and one local demo. Inspect the output before expanding the analysis. Apply your lab's standard review practices.

Contributing

Issues and pull requests are welcome in the relevant repository. Helpful contributions include public examples, clearer documentation, reproducibility fixes, and adapters for local agent workflows.

Please keep private data, credentials, and unpublished biological details out of issues, pull requests, and examples.

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  1. ferm-doe ferm-doe Public

    Fermentation and biomanufacturing experiment planning: choose design families, check scale context, and prepare run packets.

    Python 1

  2. bioprospector bioprospector Public

    Biosynthetic route exploration for target molecules: find enzyme and gene candidates and turn pathway ideas into follow-up searches and experiments.

    Python

  3. cryocore cryocore Public

    Cryo-EM workflows for maps, models, figures, state comparison, and local or cloud compute preparation.

    Python

  4. genecluster genecluster Public

    Genome-mining workflows for natural products: search public genomes and transcriptomes, compare candidate clusters, and plan follow-up work.

    Python

  5. structure-factory structure-factory Public

    AI-agent toolkit for structural biology: design binders, map structures, screen candidates, rank results, and prepare cloud-scale runs.

    Python 2

Repositories

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