diff --git a/src/Panel.tsx b/src/Panel.tsx
index 9373570..6c17c2b 100644
--- a/src/Panel.tsx
+++ b/src/Panel.tsx
@@ -39,8 +39,16 @@ const CollapsePanel = React.forwardRef<HTMLDivElement, CollapsePanelProps>((prop
       onItemClick?.(panelKey);
     },
     onKeyDown: (e: React.KeyboardEvent) => {
+      // Leave key events from nested controls (e.g. a button in `extra`) to those controls
+      if (e.target !== e.currentTarget) {
+        return;
+      }
       if (e.key === 'Enter' || e.keyCode === KeyCode.ENTER || e.which === KeyCode.ENTER) {
         onItemClick?.(panelKey);
+      } else if (e.key === ' ') {
+        // Prevent the page from scrolling, like a native button
+        e.preventDefault();
+        onItemClick?.(panelKey);
       }
     },
     role: accordion ? 'tab' : 'button',
diff --git a/tests/index.spec.tsx b/tests/index.spec.tsx
index c91c7d9..7c5d420 100644
--- a/tests/index.spec.tsx
+++ b/tests/index.spec.tsx
@@ -445,6 +445,47 @@ describe('collapse', () => {
     );
   });
 
+  it('should toggle panel when press space', () => {
+    const { container } = render(
+      <Collapse>
+        <Panel header="collapse 1" key="1">
+          first
+        </Panel>
+        <Panel header="collapse 2" key="2" collapsible="disabled">
+          second
+        </Panel>
+      </Collapse>,
+    );
+    const [header, disabledHeader] = container.querySelectorAll('.rc-collapse-header');
+
+    fireEvent.keyDown(disabledHeader, { key: ' ' });
+    jest.runAllTimers();
+    expect(container.querySelectorAll('.rc-collapse-panel-active')).toHaveLength(0);
+
+    // `fireEvent` returns false when the default action (page scroll) is prevented
+    expect(fireEvent.keyDown(header, { key: ' ' })).toBe(false);
+    jest.runAllTimers();
+    expect(container.querySelector('.rc-collapse-panel')).toHaveClass('rc-collapse-panel-active');
+
+    fireEvent.keyDown(header, { key: ' ' });
+    jest.runAllTimers();
+    expect(container.querySelectorAll('.rc-collapse-panel-active')).toHaveLength(0);
+  });
+
+  it('should leave keyboard events on a nested extra button to the button', () => {
+    const { getByRole, container } = render(
+      <Collapse
+        items={[{ key: '1', label: 'Header', extra: <button>Action</button>, children: 'Content' }]}
+      />,
+    );
+    const button = getByRole('button', { name: 'Action' });
+
+    expect(fireEvent.keyDown(button, { key: ' ' })).toBe(true);
+    fireEvent.keyDown(button, { key: 'Enter', keyCode: KeyCode.ENTER });
+    jest.runAllTimers();
+    expect(container.querySelectorAll('.rc-collapse-panel-active')).toHaveLength(0);
+  });
+
   it('should link the header to its panel with aria-controls', () => {
     const { container } = render(
       <Collapse defaultActiveKey="1">