diff --git a/driver-core/src/main/com/mongodb/internal/connection/InternalStreamConnection.java b/driver-core/src/main/com/mongodb/internal/connection/InternalStreamConnection.java
index 0cad654a73..7188c9a470 100644
--- a/driver-core/src/main/com/mongodb/internal/connection/InternalStreamConnection.java
+++ b/driver-core/src/main/com/mongodb/internal/connection/InternalStreamConnection.java
@@ -583,6 +583,12 @@ private <T> T receiveCommandMessageResponse(final Decoder<T> decoder, final Comm
             }
 
             return commandResult;
+        } catch (MongoInternalException e) {
+            if (!commandSuccessful) {
+                commandEventSender.sendFailedEvent(e);
+            }
+            close();
+            throw e;
         } catch (Exception e) {
             if (!commandSuccessful) {
                 commandEventSender.sendFailedEvent(e);
@@ -746,6 +752,10 @@ private <T> void sendCommandMessageAsync(final int messageId, final Decoder<T> d
                         commandEventSender.sendSucceededEvent(responseBuffers);
 
                         commandResult = getCommandResult(decoder, responseBuffers, messageId, operationContext.getTimeoutContext());
+                    } catch (MongoInternalException localThrowable) {
+                        close();
+                        callback.onResult(null, localThrowable);
+                        return;
                     } catch (Throwable localThrowable) {
                         callback.onResult(null, localThrowable);
                         return;
diff --git a/driver-core/src/test/unit/com/mongodb/internal/connection/InternalStreamConnectionSpecification.groovy b/driver-core/src/test/unit/com/mongodb/internal/connection/InternalStreamConnectionSpecification.groovy
index 3cdabf31da..9a68e91b64 100644
--- a/driver-core/src/test/unit/com/mongodb/internal/connection/InternalStreamConnectionSpecification.groovy
+++ b/driver-core/src/test/unit/com/mongodb/internal/connection/InternalStreamConnectionSpecification.groovy
@@ -685,6 +685,56 @@ class InternalStreamConnectionSpecification extends Specification {
         !connection.isClosed()
     }
 
+    def 'should close the connection on a responseTo mismatch'() {
+        given:
+        def connection = getOpenedConnection()
+        def pingCommandDocument = new BsonDocument('ping', new BsonInt32(1))
+        def commandMessage = new CommandMessage(database, pingCommandDocument, fieldNameValidator, primary(), messageSettings, MULTIPLE,
+                null)
+        def response = '{ok : 1}'
+        stream.getBuffer(1024) >> { new ByteBufNIO(ByteBuffer.wrap(new byte[1024])) }
+        // responseTo mismatches the actual requestId, simulating stream desynchronization
+        stream.read(16, _) >> helper.messageHeader(commandMessage.getId() + 1, response)
+        stream.read(_, _) >> helper.reply(response)
+
+        when:
+        connection.sendAndReceive(commandMessage, new BsonDocumentCodec(), OPERATION_CONTEXT)
+
+        then:
+        thrown(MongoInternalException)
+        connection.isClosed()
+    }
+
+    def 'should close the connection on an asynchronous responseTo mismatch'() {
+        given:
+        def connection = getOpenedConnection()
+        def pingCommandDocument = new BsonDocument('ping', new BsonInt32(1))
+        def commandMessage = new CommandMessage(database, pingCommandDocument, fieldNameValidator, primary(), messageSettings, MULTIPLE,
+                null)
+        def callback = new FutureResultCallback()
+        def response = '{ok : 1}'
+
+        stream.getBuffer(1024) >> { new ByteBufNIO(ByteBuffer.wrap(new byte[1024])) }
+        stream.writeAsync(_, _, _) >> { buffers, operationContext, handler ->
+            handler.completed(null)
+        }
+        stream.readAsync(16, _, _) >> { numBytes, operationContext, handler ->
+            // responseTo mismatches the actual requestId, simulating stream desynchronization
+            handler.completed(helper.defaultMessageHeader(commandMessage.getId() + 1))
+        }
+        stream.readAsync(_, _, _) >> { numBytes, operationContext, handler ->
+            handler.completed(helper.defaultReply())
+        }
+
+        when:
+        connection.sendAndReceiveAsync(commandMessage, new BsonDocumentCodec(), OPERATION_CONTEXT, callback)
+        callback.get()
+
+        then:
+        thrown(MongoInternalException)
+        connection.isClosed()
+    }
+
     def 'should notify all asynchronous writers of an exception'() {
         given:
         int numberOfOperations = 3