diff --git a/packages/browser/src/tracing/browserTracingIntegration.ts b/packages/browser/src/tracing/browserTracingIntegration.ts
index e21b40a86f27..2fa268c7332d 100644
--- a/packages/browser/src/tracing/browserTracingIntegration.ts
+++ b/packages/browser/src/tracing/browserTracingIntegration.ts
@@ -292,6 +292,10 @@ const DEFAULT_BROWSER_TRACING_OPTIONS: BrowserTracingOptions = {
   ...defaultRequestInstrumentationOptions,
 };
 
+// Bundlers can define these as `true` to tree-shake the root span error handlers and background tab detection
+declare const __SENTRY_EXCLUDE_SPAN_ERROR_INSTRUMENTATION__: boolean | undefined;
+declare const __SENTRY_EXCLUDE_BACKGROUND_TAB_DETECTION__: boolean | undefined;
+
 /**
  * The Browser Tracing integration automatically instruments browser pageload/navigation
  * actions as transactions, and captures requests, metrics and errors as spans.
@@ -431,7 +435,12 @@ export const browserTracingIntegration = ((options: Partial<BrowserTracingOption
         return;
       }
 
-      registerSpanErrorInstrumentation();
+      if (
+        typeof __SENTRY_EXCLUDE_SPAN_ERROR_INSTRUMENTATION__ === 'undefined' ||
+        !__SENTRY_EXCLUDE_SPAN_ERROR_INSTRUMENTATION__
+      ) {
+        registerSpanErrorInstrumentation();
+      }
 
       if (
         enableLongAnimationFrame &&
@@ -733,7 +742,11 @@ export const browserTracingIntegration = ((options: Partial<BrowserTracingOption
         }
       }
 
-      if (markBackgroundSpan) {
+      if (
+        markBackgroundSpan &&
+        (typeof __SENTRY_EXCLUDE_BACKGROUND_TAB_DETECTION__ === 'undefined' ||
+          !__SENTRY_EXCLUDE_BACKGROUND_TAB_DETECTION__)
+      ) {
         registerBackgroundTabDetection();
       }
 
diff --git a/packages/browser/src/tracing/request.ts b/packages/browser/src/tracing/request.ts
index 31e1b831218e..b8ab9d070a80 100644
--- a/packages/browser/src/tracing/request.ts
+++ b/packages/browser/src/tracing/request.ts
@@ -171,7 +171,10 @@ export function instrumentOutgoingRequests(client: Client, _options?: Partial<Re
           [SERVER_ADDRESS]: host,
         });
 
-        if (enableHTTPTimings) {
+        if (
+          enableHTTPTimings &&
+          (typeof __SENTRY_EXCLUDE_HTTP_TIMINGS__ === 'undefined' || !__SENTRY_EXCLUDE_HTTP_TIMINGS__)
+        ) {
           addHTTPTimings(createdSpan, client);
         }
 
@@ -192,7 +195,10 @@ export function instrumentOutgoingRequests(client: Client, _options?: Partial<Re
       );
 
       if (createdSpan) {
-        if (enableHTTPTimings) {
+        if (
+          enableHTTPTimings &&
+          (typeof __SENTRY_EXCLUDE_HTTP_TIMINGS__ === 'undefined' || !__SENTRY_EXCLUDE_HTTP_TIMINGS__)
+        ) {
           addHTTPTimings(createdSpan, client);
         }
 
@@ -204,6 +210,9 @@ export function instrumentOutgoingRequests(client: Client, _options?: Partial<Re
   }
 }
 
+// Bundlers can define this as `true` to tree-shake HTTP timing collection (`enableHTTPTimings`)
+declare const __SENTRY_EXCLUDE_HTTP_TIMINGS__: boolean | undefined;
+
 /**
  * The maximum time (ms) to wait for PerformanceResourceTiming data before ending the span.
  * Same approach is used by OTel's browser fetch instrumentation:
diff --git a/packages/browser/test/tracing/browserTracingIntegration.test.ts b/packages/browser/test/tracing/browserTracingIntegration.test.ts
index 0061ec0dde23..ff4c19028921 100644
--- a/packages/browser/test/tracing/browserTracingIntegration.test.ts
+++ b/packages/browser/test/tracing/browserTracingIntegration.test.ts
@@ -33,6 +33,8 @@ import { PREVIOUS_TRACE_TMP_SPAN_ATTRIBUTE } from '../../src/tracing/linkedTrace
 import { bfcacheMetricsIntegration } from '../../src/integrations/bfcacheMetrics';
 import * as webVitalsModule from '../../src/integrations/webVitals';
 import { getDefaultBrowserClientOptions } from '../helper/browser-client-options';
+import * as sentryCore from '@sentry/core';
+import * as backgroundTab from '../../src/tracing/backgroundtab';
 import {
   SENTRY_SEGMENT_NAME_SOURCE,
   URL_FULL,
@@ -495,6 +497,51 @@ describe('browserTracingIntegration', () => {
     );
   });
 
+  describe('tree-shakeable root span handlers', () => {
+    afterEach(() => {
+      vi.unstubAllGlobals();
+    });
+
+    function initClient(): void {
+      const client = new BrowserClient(
+        getDefaultBrowserClientOptions({
+          tracesSampleRate: 1,
+          integrations: [browserTracingIntegration()],
+        }),
+      );
+      setCurrentClient(client);
+      client.init();
+    }
+
+    it('registers span error instrumentation and background tab detection by default', () => {
+      const registerSpanErrorSpy = vi.spyOn(sentryCore, 'registerSpanErrorInstrumentation');
+      const registerBackgroundTabSpy = vi.spyOn(backgroundTab, 'registerBackgroundTabDetection');
+
+      initClient();
+
+      expect(registerSpanErrorSpy).toHaveBeenCalledOnce();
+      expect(registerBackgroundTabSpy).toHaveBeenCalledOnce();
+    });
+
+    it("doesn't register span error instrumentation if `__SENTRY_EXCLUDE_SPAN_ERROR_INSTRUMENTATION__` is true", () => {
+      vi.stubGlobal('__SENTRY_EXCLUDE_SPAN_ERROR_INSTRUMENTATION__', true);
+      const registerSpanErrorSpy = vi.spyOn(sentryCore, 'registerSpanErrorInstrumentation');
+
+      initClient();
+
+      expect(registerSpanErrorSpy).not.toHaveBeenCalled();
+    });
+
+    it("doesn't register background tab detection if `__SENTRY_EXCLUDE_BACKGROUND_TAB_DETECTION__` is true", () => {
+      vi.stubGlobal('__SENTRY_EXCLUDE_BACKGROUND_TAB_DETECTION__', true);
+      const registerBackgroundTabSpy = vi.spyOn(backgroundTab, 'registerBackgroundTabDetection');
+
+      initClient();
+
+      expect(registerBackgroundTabSpy).not.toHaveBeenCalled();
+    });
+  });
+
   describe('startBrowserTracingPageLoadSpan', () => {
     it('works without integration setup', () => {
       const client = new BrowserClient(
diff --git a/packages/browser/test/tracing/request.test.ts b/packages/browser/test/tracing/request.test.ts
index e0c8fe8f0947..ab7b78a95477 100644
--- a/packages/browser/test/tracing/request.test.ts
+++ b/packages/browser/test/tracing/request.test.ts
@@ -90,6 +90,46 @@ describe('instrumentOutgoingRequests', () => {
     expect(requestSpanJson.attributes[HTTP_REQUEST_METHOD]).toBe('QUERY');
   });
 
+  describe('HTTP timings', () => {
+    afterEach(() => {
+      vi.unstubAllGlobals();
+    });
+
+    function startFetchRequestSpan(): void {
+      let fetchHandler: ((data: utils.HandlerDataFetch) => void) | undefined;
+      vi.spyOn(utils, 'addFetchInstrumentationHandler').mockImplementation(handler => {
+        fetchHandler = handler;
+      });
+      const tracingClient = new BrowserClient(getDefaultBrowserClientOptions({ tracesSampleRate: 1 }));
+      utils.setCurrentClient(tracingClient);
+      utils._INTERNAL_setSpanForScope(utils.getCurrentScope(), new utils.SentrySpan({ sampled: true }));
+
+      instrumentOutgoingRequests(tracingClient, { traceXHR: false });
+      fetchHandler?.({
+        fetchData: { method: 'GET', url: 'https://example.com/api' },
+        args: ['https://example.com/api'],
+        startTimestamp: Date.now(),
+      });
+    }
+
+    it('collects HTTP timings by default', () => {
+      const addPerformanceSpy = vi.spyOn(browserUtils, 'addPerformanceInstrumentationHandler');
+
+      startFetchRequestSpan();
+
+      expect(addPerformanceSpy).toHaveBeenCalledWith('resource', expect.any(Function));
+    });
+
+    it("doesn't collect HTTP timings if `__SENTRY_EXCLUDE_HTTP_TIMINGS__` is true", () => {
+      vi.stubGlobal('__SENTRY_EXCLUDE_HTTP_TIMINGS__', true);
+      const addPerformanceSpy = vi.spyOn(browserUtils, 'addPerformanceInstrumentationHandler');
+
+      startFetchRequestSpan();
+
+      expect(addPerformanceSpy).not.toHaveBeenCalled();
+    });
+  });
+
   it('creates a QUERY XHR span with the QUERY method attribute', () => {
     let xhrHandler: ((data: browserUtils.HandlerDataXhr) => void) | undefined;
     let requestSpan: utils.Span | undefined;