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<!DOCTYPE html>
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<title>Publications - AGINGlab</title>
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<p> <strong>* = equal contribution</strong></p>
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<div class="pub-list">
<h3 style="text-align: left;">2025</h3>
<ul>
<li>Brzezinski-Rittner, A., Moqadam, R., Iturria-Medina, Y., Chakravarty, M. M., Dadar, M.*,
& <strong>Zeighami,
Y.*</strong> (2025). Disentangling the effect of sex from brain size on brain
organization and cognitive
functioning. GeroScience,
1-16.
<a href="https://link.springer.com/article/10.1007/s11357-024-01486-5"
target="_blank">Link</a>
</li>
<li>Moqadam, R., Azizi, H., Brzezinski-Rittner, A., Ronat, L., Hanganu, A.,
<strong>Zeighami, Y.*</strong>, &
Dadar, M*. (2025).
Apathy progression is associated with brain atrophy and white matter damage in
Parkinson’s disease. medRxiv,
2025-01.
<a href="https://www.medrxiv.org/content/10.1101/2025.01.22.25320946v2"
target="_blank">Link</a>
</li>
<li>Danyluik, M., <strong>Zeighami, Y.</strong>, Mukora, A., Lepage, M., Shah, J., Joober,
R., ... & Chakravarty,
M. M. (2025).
Evaluating permutation-based inference for partial least squares analysis of
neuroimaging data. Imaging
Neuroscience, 3, imag_a_00434.
<a href="https://direct.mit.edu/imag/article/doi/10.1162/imag_a_00434/125727"
target="_blank">Link</a>
</li>
<li>Knight, S., Abbasova, L., <strong>Zeighami, Y.</strong>, Hansen, J., Martins, D.,
Zelaya, F., ... & Modinos,
G. (2025).
Transcriptional and neurochemical signatures of cerebral blood flow alterations in
schizophrenia and individuals
at clinical high-risk for psychosis. Biological psychiatry.
</li>
</ul>
<h3 style="text-align: left;">2024</h3>
<ul>
<li>Moqadam, R., Dadar, M.*, & <strong>Zeighami, Y.*</strong> (2024). Investigating the
impact of motion in the
scanner on brain age predictions. Imaging Neuroscience, 2, 1-21.
<a href="https://direct.mit.edu/imag/article/doi/10.1162/imag_a_00079/119065"
target="_blank">Link</a>
</li>
<li>Dadar, M., Sanches, L., Fouqouet, J., Moqadam, R., Alasmar, Z., Miraut, D., ... &
<strong>Zeighami,
Y.</strong> (2024). The
Douglas Bell Canada Brain Bank Post-mortem Brain Imaging Protocol. Aperture Neuro.
<a href="https://apertureneuro.org/article/123347-the-douglas-bell-canada-brain-bank-post-mortem-brain-imaging-protocol"
target="_blank">Link</a>
</li>
<li>Ma, W., Frigon, E. M., Maranzano, J., <strong>Zeighami, Y.*</strong>, & Dadar, M.*
(2024). Differential
effects of prolonged
post-fixation on immunohistochemical and histochemical staining for postmortem human
brains. Frontiers in
Neuroanatomy, 18, 1477973.
<a href="https://www.frontiersin.org/journals/neuroanatomy/articles/10.3389/fnana.2024.1477973/full"
target="_blank">Link</a>
</li>
<li>Adame-Gonzalez, W., Brzezinski-Rittner, A., <strong>Zeighami, Y.</strong>, Chakravarty,
M. M., Farivar, R., &
Dadar, M. (2024). FONDUE:
Robust resolution-invariant denoising of MR Images using Nested UNets. Imaging
Neuroscience, 2, 1-25.
<a href="https://direct.mit.edu/imag/article/doi/10.1162/imag_a_00374/125037/FONDUE-Robust-resolution-invariant-denoising-of-MR"
target="_blank">Link</a>
</li>
<li>Pak, V., Adewale, Q., Bzdok, D., Dadar, M., <strong>Zeighami, Y.</strong>, &
Iturria-Medina, Y. (2024).
Distinctive whole-brain
cell types predict tissue damage patterns in thirteen neurodegenerative conditions.
Elife, 12, RP89368.
<a href="https://elifesciences.org/articles/89368" target="_blank">Link</a>
</li>
<li>Legault, M., Pelletier, M., Lachance, A., Lachance, M. È., <strong>Zeighami,
Y.</strong>, Gauthier, M. F., ...
& Michaud, A.
(2024). Sustained improvements in brain health and metabolic markers 24 months following
bariatric surgery.
Brain communications, 6(5), fcae336.
<a href="https://academic.oup.com/braincomms/article/doi/10.1093/braincomms/fcae336/7810953"
target="_blank">Link</a>
</li>
</ul>
<h3 style="text-align: left;">2023</h3>
<ul>
<li><strong>Zeighami, Y.</strong>, Bakken, T. E., Nickl-Jockschat, T., Peterson, Z., Jegga,
A. G., Miller, J. A.,
... & Hawrylycz,
M. (2023). A comparison of anatomic and cellular transcriptome structures across 40
human brain diseases. PLoS
biology, 21(4), e3002058.
<a href="https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002058"
target="_blank">Link</a>
</li>
<li>Xu, B., Fereshtehnejad, S. M., & <strong>Zeighami, Y.</strong> (2023). Prodromal stage
of neurodegenerative
proteinopathies:
from bench to bedside. Frontiers in Neuroscience, 17, 1295344.
<a href="https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2023.1295344/full"
target="_blank">Link</a>
</li>
<li>Khan, A. F., Adewale, Q., Lin, S. J., Baumeister, T. R., <strong>Zeighami, Y.</strong>,
Carbonell, F., ... &
Iturria-Medina, Y.
(2023). Patient-specific models link neurotransmitter receptor mechanisms with motor and
visuospatial axes of
Parkinson’s disease. Nature Communications, 14(1), 6009.
<a href="https://www.nature.com/articles/s41467-023-41677-w" target="_blank">Link</a>
</li>
<li>Kamal, F., Morrison, C., Maranzano, J., <strong>Zeighami, Y.</strong>, & Dadar, M.
(2023). White matter
hyperintensity
trajectories in patients with progressive and stable mild cognitive impairment.
Neurology, 101(8), e815-e824.
<a href="https://www.neurology.org/doi/10.1212/WNL.0000000000207514"
target="_blank">Link</a>
</li>
<li>Kamal, F., Morrison, C., Maranzano, J., <strong>Zeighami, Y.</strong>, & Dadar, M.
(2023). Topographical
differences in white
matter hyperintensity burden and cognition in aging, MCI, and AD. GeroScience, 45(1),
1-16.
<a href="https://link.springer.com/article/10.1007/s11357-022-00665-6"
target="_blank">Link</a>
</li>
<li>Morys, F., Potvin, O., <strong>Zeighami, Y.</strong>, Vogel, J., Lamontagne-Caron, R.,
Duchesne, S., ... &
Alzheimer’s Disease
Neuroimaging Initiative. (2023). Obesity-associated neurodegeneration pattern mimics
Alzheimer’s disease in an
observational cohort study. Journal of Alzheimer’s Disease, 91(3), 1059-1071.
<a href="https://journals.sagepub.com/doi/full/10.3233/JAD-220535"
target="_blank">Link</a>
</li>
<li>Wang, Q., Aljassar, M., Bhagwat, N., <strong>Zeighami, Y.</strong>, Evans, A. C.,
Dagher, A., ... & Poline, J.
B. (2023).
Reproducibility of cerebellar involvement as quantified by consensus structural MRI
biomarkers in advanced
essential tremor. Scientific Reports, 13(1), 581.
<a href="https://www.nature.com/articles/s41598-022-25306-y" target="_blank">Link</a>
</li>
</ul>
<h3 style="text-align: left;">2022</h3>
<ul>
<li><strong>Zeighami, Y.</strong>, Dadar, M., Daoust, J., Pelletier, M., Biertho, L.,
Bouvet-Bouchard, L., ... &
Michaud, A.
(2022). Impact of weight loss on brain age: Improved brain health following bariatric
surgery. Neuroimage, 259,
119415.
<a href="https://www.sciencedirect.com/science/article/pii/S1053811922005328"
target="_blank">Link</a>
</li>
<li>Garcia-Garcia, I., Neseliler, S., Morys, F., Dadar, M., Yau, Y. H., Scala, S. G.,
...,<strong>Zeighami,
Y.</strong> & Dagher, A. (2022).
Relationship between impulsivity, uncontrolled eating and body mass index: a
hierarchical model. International
Journal of Obesity, 46(1), 129-136.
<a href="https://www.nature.com/articles/s41366-021-00966-4" target="_blank">Link</a>
</li>
<li>Garcia-Garcia, I., Neseliler, S., Morys, F., Dadar, M., Yau, Y. H., Scala, S.
G.,<strong>Zeighami, Y.</strong>
& Dagher, A. (2022).
Relationship between impulsivity, uncontrolled eating and body mass index: a
hierarchical model. International
Journal of Obesity, 46(1), 129-136.
<a href="https://www.nature.com/articles/s41366-021-00966-4" target="_blank">Link</a>
</li>
<li>Lenglos, C., Lin, S. J., <strong>Zeighami, Y.</strong>, Baumeister, T. R., Carbonell,
F., & Iturria-Medina, Y.
(2022).
Multivariate genomic and transcriptomic determinants of imaging-derived personalized
therapeutic needs in
Parkinson’s disease. Scientific Reports, 12(1), 5483.
<a href="https://www.nature.com/articles/s41366-021-00966-4" target="_blank">Link</a>
</li>
<li>Kirschner, M., Schmidt, A., Hodzic-Santor, B., Burrer, A., Manoliu, A., c, ... &
Kaiser, S. (2021).
Orbitofrontal-striatal structural alterations linked to negative symptoms at different
stages of the
schizophrenia spectrum. Schizophrenia bulletin, 47(3), 849-863.
<a href="https://academic.oup.com/schizophreniabulletin/article-abstract/47/3/849/6012978"
target="_blank">Link</a>
</li>
<li>Zhernovaia, M., Dadar, M., Mahmoud, S., <strong>Zeighami, Y.</strong>, & Maranzano, J.
(2022). The
PaleoArchiNeo (PAN) human
brain atlas: A dataset on a standard neuroanatomical MRI template following a
phylogenetic approach. Data in
Brief, 41, 107863.
<a href="https://www.sciencedirect.com/science/article/pii/S2352340922000750"
target="_blank">Link</a>
</li>
</ul>
<h3 style="text-align: left;"> Selcted Publications from 2021 and before</h3>
<ul>
<li><strong>Zeighami, Y.</strong>, Iceta, S., Dadar, M., Pelletier, M., Nadeau, M., Biertho,
L., ... & Michaud, A. (2021).
Spontaneous neural activity changes after bariatric surgery: A resting-state fMRI study.
Neuroimage, 241,
118419.
<a href="https://www.sciencedirect.com/science/article/pii/S1053811921006947"
target="_blank">Link</a>
</li>
<li><strong>Zeighami, Y.</strong>, & Evans, A. C. (2021). Association vs. prediction: the
impact of cortical surface smoothing and
parcellation on brain age. Frontiers in big Data, 4, 637724.
<a href="https://www.frontiersin.org/articles/10.3389/fdata.2021.637724/full"
target="_blank">Link</a>
</li>
<li><strong>Zeighami, Y.</strong>, Fereshtehnejad, S. M., Dadar, M., Collins, D. L.,
Postuma, R. B., Mišić, B., & Dagher, A.
(2019). A clinical-anatomical signature of Parkinson's disease identified with partial
least squares and
magnetic resonance imaging. Neuroimage, 190, 69-78.
<a href="https://www.sciencedirect.com/science/article/abs/pii/S1053811917310741?via%3Dihub"
target="_blank">Link</a>
</li>
<li><strong>Zeighami, Y.*</strong>, Pandya, S.*, Freeze, B., Dadar, M., Collins, D. L.,
Dagher, A., & Raj, A. (2019). Predictive
model of spread of Parkinson's pathology using network diffusion. NeuroImage, 192,
178-194.
<a href="https://linkinghub.elsevier.com/retrieve/pii/S1053811919301685"
target="_blank">Link</a>
</li>
<li><strong>Zeighami, Y.</strong>, Fereshtehnejad, S. M., Dadar, M., Collins, D. L.,
Postuma, R. B., & Dagher, A. (2019).
Assessment of a prognostic MRI biomarker in early de novo Parkinson's disease.
NeuroImage: Clinical, 24, 101986.
<a href="https://www.sciencedirect.com/science/article/pii/S2213158219303365"
target="_blank">Link</a>
</li>
<li><strong>Zeighami, Y.*</strong>,Yau, Y.*, Baker, T. E., Larcher, K., Vainik, U., Dadar,
M., ... & Dagher, A. (2018). Network
connectivity determines cortical thinning in early Parkinson’s disease progression.
Nature communications, 9(1),
12.
<a href="https://www.nature.com/articles/s41467-017-02416-0" target="_blank">Link</a>
</li>
<li>Fereshtehnejad, S. M., <strong>Zeighami, Y.</strong>, Dagher, A., & Postuma, R. B.
(2017). Clinical criteria for subtyping
Parkinson’s disease: biomarkers and longitudinal progression. Brain, 140(7), 1959-1976.
<a href="https://academic.oup.com/brain/article-abstract/140/7/1959/3855005"
target="_blank">Link</a>
</li>
<li><strong>Zeighami, Y.</strong>, & Moustafa, A. A. (2015). Differential functions of
ventral and dorsal striatum. Brain, 138(10), e381-e381.
<a href="https://academic.oup.com/brain/article-abstract/138/10/e381/2468692"
target="_blank">Link</a>
</li>
<li><strong>Zeighami, Y.</strong>, Ulla, M., Iturria-Medina, Y., Dadar, M., Zhang, Y.,
Larcher, K. M. H., ... & Dagher, A. (2015).
Network structure of brain atrophy in de novo Parkinson's disease. elife, 4, e08440.
<a href="https://elifesciences.org/articles/8440" target="_blank">Link</a>
</li>
</ul>
</div>
</div>
<div class="tab-pane fade" id="conferences" role="tabpanel" aria-labelledby="conferences-tab">
<div class="pub-list">
<h3 style="text-align: left;"> 2024</h3>
<ul>
<li>Brzezinski-Rittner A, Dadar M, Zeighami, Y. Disentangling the Effect of Brain Size from
Sex Differentiated Aging Trajectories. 2024 OHBM Annual Meeting, Seoul, Korea. (Poster)
</li>
<li>Moqadam R, Azizi H, Brzezinski-Rittner A, Hanganu A, Zeighami Y, Dadar M. Investigating
the
relation between white matter hyperintensities burden and the severity of Apathy score
in
Parkinson’s disease. 2024 OHBM Annual Meeting, Seoul, Korea. (Poster)
</li>
<li>Metz, A., Zeighami, Y., Ducharme, S., Villeneuve, S., & Dadar, M. (2024, June 24/25).
Association between DBM-derived Atrophy Patterns and Cognition in Frontotemporal
Dementia Variants [Poster Abstract and Presentation]. 2024 OHBM Annual Meeting, Seoul,
Korea. (Poster)
</li>
<li>Walter Adame-Gonzalez, Moqadam, R., Zeighami, Y., & Dadar, M. (2024, June). Fast and
robust structural MRI super-resolution using voxel-size independent GANs. 2024 OHBM
Annual Meeting, Seoul, Korea. (Poster)
</li>
<li>Alasmar, Z., Moqadam, R., Guerra-Sanches, L., Zeighami, Y.*, Dadar, M.* (2024). Fixation
Duration Effects on Microstructural Changes in Disease: Insight from Ex-vivo Diffusion
MRI. 2024 OHBM
Annual Meeting, Seoul, Korea. (Poster)
</li>
</ul>
<!-- Conference publications go here -->
</div>
</div>
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